Phospho-4ebp1
WebMay 19, 2015 · Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors PLoS One doi: 10.1371/journal.pone.0127123. eCollection 2015. Authors WebSep 11, 2024 · Glioblastoma is the most common malignant primary brain tumor, and it is one of the causes of cancer fatality in both adult and pediatric populations. Patients with glioblastoma require chemotherapy after surgical resection and radiotherapy. Therefore, chemotherapy constitutes a viable approach for the eradication of glioblastoma cells. In …
Phospho-4ebp1
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WebPrimary Antibodies (9010) Secondary Antibodies (76) Antibody Conjugates (1994) Activators & Inhibitors (224) Buffers & Dyes (108) Cellular Assay Kits (118) ChIP Kits & Reagents (156) CUT&RUN Kits & Reagents (15) Cytokines & Growth Factors (215) ELISA Kits (513) Experimental Controls (248) Flow Cytometry Kits & Reagents (9) Proteomic Analysis … WebJan 2, 2024 · Here we demonstrate that rapamycin-insensitive mTORC1 signaling via 4E-BP1 is a critical pathway for TGF-β 1 stimulated collagen synthesis in human lung fibroblasts, whereas canonical PI3K/Akt...
WebPhospho-4EBP1 (Thr46) Antibody (44-1170G) in ICC/IF Immunofluorescence analysis of 4EBP1 (pT46) was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.25% Triton™ X-100 for 10 minutes, and blocked with 5% BSA for 1 hour at room temperature. WebPhospho-4EBP1 (Thr37, Thr46) Antibody (MA5-36936) in Flow Flow cytometry of Phospho-EIF4EBP1 (Thr37, Thr46) using Jurkat cells. Samples were incubated in monoclonal Phospho-EIF4EBP1 (Thr37, Thr46) antibody ( Product # MA5-36936 ).
Web当你希望让更多商家联系你时,可以勾选后发送询价,平台会将你的询价消息推荐给更多商家。 WebDec 24, 2008 · Cytoplasmic p-4EBP1 and p-mTOR expression was not related to each other (P > 0.05, data not shown). Expression of p-mTOR and phospho-4EBP1 is increased in high-risk tumors. Endometrial adenocarcinomas can be characterized by a variety of clinical and pathological parameters, which help to estimate cancer behavior.
WebMar 22, 2024 · DRAM1 also dramatically downregulated the phosphorylation of both rpS6 at Ser 240/244 (Fig. 2 a and c) and 4EBP1 (Fig. 2 a and d), suggesting that the activity of p70S6K was decreased, though the phosphorylation of mTOR itself had no change (Fig. 2 a).
Web丁香通为您提供4EBP1antibod商品详情介绍:价格:询价,货号:GTX83226,CAS号:详见说明书,品牌:慧嘉生物,产地:USA,详见丁香通4EBP1antibod商品详情页; iron rich vegetarian foods for anemiaWebApr 1, 2024 · We also engineered a mutant 4E-BP1 that cannot be phosphorylated by mTOR resembling de-phospho-Thr46-4E-BP1, and generated HNSCC cells expressing this mutant in a tetracycline-inducible fashion. Expression of 4E-BP1 M was sufficient to disrupt the function of the translation–initiation complex, and resulted in tumor regression in HNSCC ... iron rich vegetarian foods during pregnancyWebPhospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb detects endogenous levels of 4E-BP1 only when phosphorylated at Thr37 and/or Thr46. This antibody may cross-react with 4E-BP2 … iron ridge campground reservationsWeb实验用到的供体是Thr46(铽标记的anti-phospho-4EBP1),受体是绿色荧光标记的4EBP1,是mTOR下游信号通路的蛋白,有活性的mTOR能磷酸化4EBP1,使之与供体结合。如果mTOR活性受到抑制,供体受体距离不能达到荧光能量转移的要求,则在515nm处与485nm处的信号比值增大。 iron ridge apts spearfish sdWebThe ER is the main organelle for calcium (Ca 2+) storage in cells.Its physiological function is closely related to Ca 2+ homeostasis (Wong et al., 1993).To investigate the effect of As 3+ /Se 4+ combination on ER function, this study pretreated cells with ERS inducer thapsigargin (TG) and ERS inhibitor 2-aminoethoxydiphenyl borate (2-APB), followed by Fluo-3-AM and … iron richard bourkeWebMolecular Cell, Vol. 12, 889–901, October, 2003, Copyright 2003 by Cell Press Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential port royal hotel wildwood crest nj reviewsWebApr 14, 2024 · Neuropathic pain caused by trigeminal nerve injury is a typical refractory orofacial chronic pain accompanied by the development of hyperalgesia and allodynia. … port royal hotel wildwood crest nj restaurant