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High affinity copper uptake protein

High affinity copper uptake protein 1 (CTR1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, … Ver mais In 2024, a new autosomal-recessive disease was discovered that is caused by mutations of the CTR1 gene. The disease is characterized by profound deficiency of copper in the central nervous system and presents with … Ver mais • Solute carrier family Ver mais • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". … Ver mais WebHigh-affinity, saturable copper transporter involved in dietary copper uptake. go to UniProt 3D viewer pLDDT corresponds to the model’s prediction of its score on the local …

JoF Free Full-Text Multicopper Oxidases in Saccharomyces …

Web1 de abr. de 2014 · As previously mentioned, high-affinity Fe uptake at the plasma membrane depends in S. cerevisiae on Fet3 ferroxidase, which uses Cu as an indispensable cofactor for its activity. Therefore, Cu deficiency leads to impaired Fe transport in yeast, and consequently to multiple Fe-related symptoms [ 61 ]. WebLOC108023471 high affinity copper uptake protein 1 [] Gene ID: 108023471, updated on 15-Oct-2024. Summary Other designations. high affinity ... how come harry potter didn\u0027t die https://todaystechnology-inc.com

Interactions of TonB-dependent transporter FoxA with …

Web27 de abr. de 2024 · In silico analysis has revealed three ferroxidase genes, namely CgFET3 (high affinity iron uptake; 70% similarity with ScFET3), ... Rydén, L.G.; Hunt, L.T. Evolution of protein complexity: The blue copper-containing oxidases and related proteins. J. Mol. Evol. 1993, 36, 41–66. Web16 de mar. de 2010 · Copper and iron are essential elements employed in pathways that are conserved in all kingdoms of life. In eukaryotes, several interdependent connections between copper and iron homeostasis have been described previously ().For example, high-affinity iron uptake in Saccharomyces cerevisiae is mediated by multicopper … Web1 de out. de 2002 · High affinity copper uptake protein 1 Gene Slc31a1 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 196 Protein … how come green tea can look yellow

The SLC31 (Ctr) copper transporter family - PubMed

Category:Arabidopsis COPT1 copper transporter uses a single histidine to ...

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High affinity copper uptake protein

Characterization of the Saccharomyces cerevisiae High …

Web30 de dez. de 2005 · High affinity copper binding by wild type PrP has been confirmed by the independent techniques indicating the presence of specific tight copper binding sites … WebCTR1, high affinity copper uptake protein 1; ATP7A, copper-transporting ATPase 1; CCO, cytochrome C oxidase; ATOX1, copper transport protein ATOX1; KRAS, Kirsten rat sarcoma 2 viral oncogene homolog. Display full size. Figure 1. KRAS-driven colorectal cancer (CRC) cells are addicted to copper metabolism.

High affinity copper uptake protein

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Web5 de jun. de 2001 · Copper serves as an essential cofactor for a variety of proteins in all living organisms. Previously, we described a human gene (CTR1;SLC31A1)that encodes a high-affinity copper-uptake protein and hypothesized that this protein is required for copper delivery to mammalian cells. WebLOC106158117 high affinity copper uptake protein 1 [] Gene ID: 106158117, updated on 12-Aug-2024. Summary Other designations. high affinity ...

WebAlternate Antibody Name: Alternate Gene Names: Solute Carrier Family 31 (Copper Transporter), Member 1; COPT1; CTR1; Copper Transporter 1; Solute Carrier Family 31 … Web12 de out. de 2012 · The Ctr1 gene encodes a multispanning plasma membrane protein of 460 amino acids and is a necessary factor in high affinity copper uptake and supplies copper for all known copper-dependent physiological processes (Georgatsou et al., 1997, Sinani et al., 2007, Nakagawa et al., 2010).

WebChimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562COPPER (I) IONZINC ION NCBI National Center forBiotechnology Information Search 6M98: Crystal structure of the high-affinity copper transporter Ctr1 in complex with Cu(I) Biological Unit for 6M98: trimeric; determined by author and by software (PISA) WebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function

Webencode a high affinity copper uptake process and was found to be 29% identical at the primary structure level with Ctr1 from yeast. The human protein was, however, substantially smaller than the yeast protein, being composed of 190 amino acids as compared with 406 amino acids (see Fig. 1). hCTR1 is on the

WebOne way that some methanotrophs obtain copper is by production and secretion of methanobactins (Mbns), ribosomally synthesized, posttranslationally modified peptide natural products that bind Cu I with high affinity ().The protein machinery to manufacture and transport Mbns is encoded by operons, which are down-regulated under copper … how come he don\\u0027t want meWeb12 de abr. de 2024 · To overcome this challenge, bacteria synthesize high-affinity iron-binding molecules called siderophores, which are recognized by specific transporters on … how come harry potter didn\\u0027t dieWeb12 de abr. de 2024 · To overcome this challenge, bacteria synthesize high-affinity iron-binding molecules called siderophores, which are recognized by specific transporters on the cell surface. Trojan horse antibiotics have evolved to hijack these transporters for uptake across the outer membrane (OM). how many poker chips for 8 playersWebLOC100178573 high affinity copper uptake protein 1-like [ (vase tunicate)] Gene ID: 100178573, updated on 26-Oct-2024. Summary Other designations. high affinity ... how come girls don\\u0027t like meWebWe ascertain the ability of these proteins to functionally complement and transport copper in the corresponding Saccharomyces cerevisiae high-affinity copper transport mutant. The specific expression pattern of the Arabidopsis COPT1–5 mRNA in different tissues was analyzed by RT-PCR. how come hdmi doesnt work on my pc windows 7Web30 de mar. de 2024 · Functional assays revealed that it stimulates the initial rate of radiolabeled copper uptake. CTR1 transports copper with high affinity in a time-dependent and saturable manner and is copper-specific. Transport is an energy-independent process and is stimulated by extracellular acidic pH and high K+ … how many poker chips per personWebProtein target information for High affinity copper uptake protein 1 (Norway rat). Find diseases associated with this biological target and compounds tested against it in … how many poker tables at foxwoods