WebOct 16, 2024 · Similarly, GETUG–AFU 17, involving 424 patients, revealed no significant difference in 5-year EFS (92% in the adjuvant radiotherapy group versus 90% in the early salvage group, HR 0.81, log-rank ... WebAt database lock on Dec 19, 2024, the overall median follow-up time from random assignment was 75 months (IQR 50-100), 74 months (47-100) in the adjuvant radiotherapy group and 78 months (52-101) in the salvage radiotherapy group. In the salvage radiotherapy group, 115 (54%) of 212 patients initiated study treatment after …
Early Salvage Therapy for Patients With Advanced Features for ...
WebTherefore, we must decide if we are going to treat patients in the early or later salvage radiotherapy setting. Data from Tendulkar et al. 1 suggest that higher pre-salvage radiotherapy PSAs lead to worse freedom from biochemical failure: However, based on early PSMA PET/CT data, Dr. Parker questions whether we can potentially wait to treat ... WebOct 19, 2024 · We aimed to compare adjuvant versus early salvage radiotherapy after radical prostatectomy, combined with short-term hormonal therapy, in terms of oncological outcomes and tolerance. METHODS. GETUG-AFU 17 was a randomised, open-label, multicentre, phase 3 trial done at 46 French hospitals. Men aged at least 18 years who … the george vets nailsworth
Frühe Salvage-Bestrahlung der Prostataloge scheint ... - Springer
WebSep 28, 2024 · This collaborative and prospectively designed systematic review and meta-analysis suggests that adjuvant radiotherapy does not improve event-free survival in … Regarding early efficacy outcome measures, 169 biochemical progression … WebApr 10, 2024 · The ability of early salvage radiotherapy to control recurrent disease in 50% of men with recurrent prostate cancer is very similar to the 50% relative reduction in BCR seen in patients treated with adjuvant radiotherapy in the SWOG 8794, EORTC 22911 and ARO 96-02 trials. With the highly sensitive PSA assays that are available, recurrent … WebSep 12, 2024 · However, in men receiving early salvage radiotherapy (PSA ≤0.6 ng/mL) in RTOG 9601, post-hoc analyses found long-term antiandrogen treatment was not associated with improved OS due to an increased combined odds of grades 3 to 5 cardiac and neurological events (JAMA Oncol. 2024;6:735–743). Longer follow-up data from … the app show