Dibutyl phthalate renal fibrosis
WebUp to 125 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode £. (APF = 25) Any powered, air-purifying respirator with a high-efficiency … WebDec 21, 2024 · Dibutyl phthalate occurs as an odorless, oily, colorless, or very slightly yellow-colored, viscous liquid. Physical properties Colorless to pale yellow, oily, viscous liquid with a mild, aromatic odor Uses Di-n-butyl phthalate has been used as an insect repellant. Uses A phthalate metabolite with genotoxic effect. Uses
Dibutyl phthalate renal fibrosis
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WebDibutyl phthalate (DBP) and benzo(a)pyrene (BaP) are widespread environmental and foodborne contaminants that have detrimental effects on human health. Although people are often simultaneously exposed to DBP and BaP via the intake of polluted food and water, the combined effects on the kidney and potential mechanisms remain unclear. WebOct 1, 2024 · Maternal exposure to di-n-butyl phthalate (DBP) can cause renal fibrosis in adult offspring rats. However, its underlying mechanisms have not yet been fully …
WebSep 1, 2024 · However, few reports have described the specific effect of DBP on renal cells during kidney fibrosis. Recently, we reported that maternal exposure to DBP led to renal dysplasia and fibrosis in surviving adult offspring [ 1, 3 ]. Autophagy is commonly considered a protective mechanism in response to different cellular stresses and injuries. Web15 hours ago · Humans are often simultaneously exposed to benzo ( a )pyrene (BaP) and dibutyl phthalate (DBP) through consumption of food and water. Yet, direct evidence of the link between BaP and DBP co-exposure and the risk of splenic injury is lacking.
WebPrimary uses for dibutyl phthalate are to soften and increase plastic flexibility, for example, in shower curtains, raincoats, food wraps, and car interiors to name a few. It has been … WebDibutyl phthalate was detected in some drinking water supplies at levels ranging from 0.1 to 5 ppb. (1) Assessing Personal Exposure Tests are available that can detect dibutyl phthalate in blood and body tissues, and the major breakdown products of dibutyl …
WebResults showed that prenatal exposure to DBP may generate oxidative stress in both renal fibroblasts and tubular epithelial cells, leading to kidney dysplasia and renal fibrosis, whereas vitamin C ameliorated the changes caused by DBP. This study was to determine the impact of maternal exposure to di-n-butyl phthalate (DBP) on renal development …
WebDBP (dibutyl phthalate) and DEHP (di-2-ethylhexyl phthalate), which the U.S. Food and Drug Administration (FDA) recommends not be used in drugs, are not in pancreatic … csi online libraryWebFor: Yang Q, Han B, Li S, Wang X, Wu P, Liu Y, Li J, Han B, Deng N, Zhang Z.The link between deacetylation and hepatotoxicity induced by exposure to hexavalent chromium. Journal of Advanced Research 2024. [DOI: 10.1016/j.jare.2024.04.002] [Cited by in Crossref: 24] [Cited by in F6Publishing: 18] [Article Influence: 12.0] … csi online course high schoolWebMar 10, 2024 · PDF This study was to determine the impact of maternal exposure to di-n-butyl phthalate (DBP) on renal development and fibrosis in adult offspring.... Find, … csi online learningWebBACKGROUND: We previously demonstrated that maternal exposure to di-n-butyl phthalate (DBP) induces dysplasia of the kidney in newborn male offspring and renal fibrosis in adults.But the underlying mechanisms remain elusive. Fgf10/Fgfr2 and androgen receptor (AR) are known to be important for renal development. eagle farm milton mahttp://ctdbase.org/detail.go?acc=D003993&view=disease&page=5&type=chem csi online eyewitness basics answersWebFgfr2 may be involved in kidney abnormal development induced by DBP [27]. In this study, we used an optimized treatment regimen to show that maternal DBP exposure can … eagle farm post officeWebJan 31, 1987 · Nov 2012: An Approach for Integrating Toxicogenomic Data in Risk Assessment: The Dibutyl Phthalate Case Study (Journal) Dec 2008: Phthalates and … eagle family medicine village