Chitinase-3-like protein 1

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August undefined, 2024

WebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and non-coding RNAs is dysregulated during disease development. We aimed to examine a possible regulatory axis implemented in the control of chitinase-3 like protein 1 … WebWe investigated the effect of chitinase-3-like protein 1 (CHI3L1) on glucose metabolism and its underlying mechanisms in skeletal muscle cells, and evaluated whether the …

Frontiers Chitinase-3 like-protein-1, matrix metalloproteinase -9 …

WebUrine chitinase 3-like. Background Acute kidney injury (AKI) is a frequently occurring syndrome in critically ill patients and is associated with worse outcomes. Biomarkers … WebJohansen and Carretta et al. found that COS exerted their anti-tumorigenic effects through the inhibition of YKL-40 (also known as chitinase-3-like 1 or Chi3L1), which is a conserved, secreted chitinase-like protein (CLP) found in elevated levels in many diseases, including cancer [126,127]. highties ottawa

Chitinases and Chitinase-Like Proteins in Obstructive Lung …

WebDiagnosis of cardiac surgery-associated acute kidney injury: differential roles of creatinine, chitinase 3-like protein 1 and neutrophil gelatinase-associated lipocalin: a prospective … WebAnti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY. Compare Product No. Clonality Application Species Reactivity Citations SDS; MABC196: mAY, monoclonal: IHC, WB, activity assay: human: 6: Expand. Hide. Match Criteria: Product Name, Keyword. All Photos (1) Human CHI3L1 / Chitinase-3-like Protein 1 ELISA Kit. Compare Product No ... WebUrine chitinase 3-like. Background Acute kidney injury (AKI) is a frequently occurring syndrome in critically ill patients and is associated with worse outcomes. Biomarkers allow early identification and therapy of AKI which may improve outcomes. ... Urinary cell cycle arrest biomarkers and chitinase 3-like protein 1 (CHI3L1) to detect acute ... small shower ensuite ideas

Chitinase 3 Like Protein 1 - an overview ScienceDirect …

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WebChitinase 3-like 1: Products. Chitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils ... WebChitinase 3-like 1 (CHI3L1) is a chitinase-like protein, which affects cel … The cancer‑stromal interaction has been demonstrated to promote tumor progression, and … highties rideauWebJun 11, 2014 · Chitinase 3-like 1 (CHI3L1) is a prototypic chitinase-like protein that has been retained over species and evolutionary time. However, the regulat … Epithelial injury, alternative macrophage accumulation, and fibroproliferation coexist in the lungs of patients with idiopathic pulmonary fibrosis (IPF). small shower ensuite

"WebMar 4, 2024 · Chitinase-3-like protein 1 (CHI3L1) was induced in both acute and chronic liver injuries, and recent studies reported that it possesses an immunosuppressive ability. CHI3L1 was also expressed in mesenchymal stem cells (MSCs), thus we investigates the role of CHI3L1 in MSC-based therapy for immune-mediated liver injury here. We found … " - Chitinase-3-like protein 1

Chitinase-3-like protein 1

WebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies … WebThe human homologue chitinase 3-like protein 1 was found to be more excreted in urine from septic patients with AKI than without. In summary, urinary chitinase 3-like protein 1 and -3 and acidic mammalian chitinase discriminated sepsis from sepsis-induced AKI in mice. Further studies of human chitinase proteins are likely to lead to additional ...

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WebFeb 1, 2024 · The differentially secreted proteins of M1 and M2 macrophages were analyzed by mass spectrometry. We performed GST pull-down assay for the identification of cell-membrane receptors that interact with chitinase 3-like protein 1 (CHI3L1) protein. The mouse model was used to validate the function of CHI3L1 in cancer metastasis in vivo. WebMar 2, 2024 · Chitinase-3-like protein 1 (CHI3L1/YKL-40) has long been known as a biomarker for early detection of neuroinflammation and disease diagnosis of Alzheimer's disease (AD). In the brain, CHI3L1 is primarily provided by astrocytes and heralds the reactive, neurotoxic state triggered by inflammation and other stress signals. ...

WebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic … WebChitinase-3-Like Protein 1 Cysteine-Rich Protein 61 Cytokines IL15 protein, human IL6 protein, human Interleukin-15 Interleukin-6 Muscle Proteins fibroblast growth factor 21 Connective Tissue Growth Factor Fibroblast Growth Factors ...

WebJul 6, 2024 · Here, we show that chitinase-3-like 1 (CHI3L1), also known as human homolog YKL-40, predominately modulates the GBM TME using unbiased approaches. CHI3L1 signaling selectively regulates tumor infiltration and cell migration of MDMs and MG by forming distinct protein-binding complexes. WebIntroduction. Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40 and human cartilage glycoprotein-39 (HC-gp39), is a highly conserved glycoprotein that can bind to heparin, chitin and collagen. 1,2 CHI3L1 plays an important role in tissue inflammation, tissue remodeling, fibrosis and cancer. 3–5 Current studies have reported that serum …

WebChitinase 3-like 1: Products. Chitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family …

WebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies have identified chitinase-3 like-protein-1 (YKL-40) and matrix metalloproteinase (MMP)-9 as circulating inflammatory factors involved in positive vascular remodelling. Herein, we … small shower dark tileWebChitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show … highties wixWebNational Center for Biotechnology Information small shower faucetWebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and non-coding RNAs is dysregulated during disease development. We aimed to examine a … highties tenthlineWebChitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N … small shower filterWebBackground: Chitinase 3-like 1 protein (CHI3L1) (YKL-40 in humans and breast regression protein [BRP]-39 in mice) is required for optimal allergen sensitization and Th2 inflammation in various chronic inflammatory diseases including asthma. However, the role of CHI3L1 in airway inflammation induced by respiratory viruses has not been investigated. small shower dimensions in inchesWebDec 1, 2024 · Chitinase-3 like-protein-1 (CHI3L1), a member of glycoside hydrolase family 18 including chitinases and non-enzymatic chitinase-like proteins, is a secreted molecule that plays an important role in cancer development, inflammatory diseases and oxidant injury via various mechanisms [8]. small shower curtain clawfoot