Can divalproex cause thrombocytopenia

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WebFeb 23, 2024 · bleeding problems and low blood platelet levels; high blood ammonia levels; hypothermia ... Depakote or Depakote ER can cause pancreatitis, which can be life … WebMay 5, 2024 · Valproic acid (Depakote) is an antiepileptic drug approved for the treatment of bipolar disorder, migraine prophylaxis, and seizure disorders. While the exact …

Identifying drugs that cause acute thrombocytopenia: an analysis using ...

WebDec 30, 2024 · It's likely that a routine blood test showing a high platelet count will be your first indication that you have thrombocytosis. Besides taking your medical history, examining you physically and running tests, your doctor might ask about factors that could affect your platelets, such as a recent surgery, a blood transfusion or an infection. WebMar 1, 2024 · Thrombocytopenia (low platelet count) or Viral infection (eg, HIV, cytomegalovirus infection)—Use with caution. May make these conditions worse. Liver disease or ... Divalproex sodium may cause serious allergic reactions affecting multiple … Divalproex sodium is used to treat certain types of seizures (epilepsy). This … fit t shirt women\u0027s

Would taking depakote cause both low platelets and low ... - HealthTap

WebMethods: Patients with refractory partial epilepsy were enrolled in this double-blind, multicenter, concentration-response trial that evaluated the efficacy and safety of high … WebFeb 23, 2024 · Yes, it’s possible for Depakote and Depakote ER to cause long-term side effects. Liver damage, including liver failure, has been reported. Pancreatitis (swelling and damage of the pancreas)... WebCommon causes of thrombocytopenia. Primary immune thrombocytopenia (ITP) Drug-induced immune thrombocytopenia (DITP) Heparin (NOTE: special case, also can … can i get ssd for heart attack

Valproic Acid-Induced Thrombocytopenia-Related …

divalproex oral - Uses, Side Effects, and More - WebMD

WebNov 30, 2024 · Patients with DITP develop a drop in platelet count 5 to 10 days after drug administration with an increased risk of hemorrhage. The diagnosis of DITP is often … Web• Pregnancy: Depakote can cause congenital malformations including neural tube defects. Pregnancy registry available (5.2, 8.1) • Pediatric: Children under the age of two years are at considerably higher risk of fatal hepatotoxicity (5.1, 8.4) • Geriatric: reduce starting dose; increase dosage more slowly; monitor fitts industriesWebDec 30, 2024 · Valproic acid is a highly protein-bound drug. Serum levels of 50-100 mcg/mL are considered therapeutic, with minimal risk of toxicity when maintained within the … fitt sheet

"WebDec 19, 2024 · The exact mechanism through which valproate can cause thrombocytopenia is unknown; it can be caused by an increased disruption of platelets as well as by the formation of autoantibodies destroying platelets or by decreased production due to a direct toxic effect on bone marrow [ 3 ]. " - Can divalproex cause thrombocytopenia

Can divalproex cause thrombocytopenia

Divalproex Sodium (Oral Route) Before Using - Mayo Clinic

WebNov 2, 2024 · Along with its needed effects, divalproex sodium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need … WebAug 17, 2024 · Bottom Line. Divalproex may be used for the treatment of absence or partial seizures, as a preventive treatment for migraine, and to treat mania associated with …

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WebApr 19, 2024 · Thrombocytopenia rarely is inherited; or it can be caused by a number of medications or conditions. Whatever the cause, circulating platelets are reduced by one or more of the following processes: … WebBleeding and other hematopoietic disorders; monitor platelet counts and coagulation tests ( 5.8) ... Stopping divalproex sodium extended-release tablets suddenly can cause serious problems. Divalproex sodium extended-release tablets can cause serious side effects, including: Serious liver damage that can cause death, especially in children ...

WebMar 1, 2024 · The probability of thrombocytopenia increases significantly at total trough valproate plasma concentrations above 110 mcg/mL in females and 135 mcg/mL in males. The benefit of improved seizure … WebDrinking a lot of alcohol may cause your platelet level to drop. Toxic chemicals : Exposure to toxic chemicals, including arsenic, benzene and pesticides, may affect your platelet …

WebJun 27, 2024 · Unexplained thrombocytopenia is a common clinical problem, and the possibility of drug-induced thrombocytopenia must be considered, especially in … WebNov 27, 2024 · Rarely, yes: Most people who take Depakote ( valproic acid) have no impact on their blood. Some people, however, can develop low platelets or low neutrophils or both. Of course, those blood problems may also occur to people taking Depakote but be completely unrelated to the drug. A hematologist is the doctor to sort out the question.

WebMar 1, 2024 · Valproic acid is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Valproic acid is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches.

WebDec 19, 2024 · Valproate is an effective anti-epileptic and mood stabilizer drug, but its prescription may be complicated by the development of thrombocytopenia. The … can i get ss disability and ssWebApr 2, 2024 · Thrombocytopenia is a condition that develops because your body does not have enough platelets. Platelets are cells that help your blood to clot. Your body may not be making enough platelets, or it may be destroying too many platelets. When platelets become low, your risk for bleeding increases. Severe bleeding may become life-threatening. fitts industries inc can i get ss and still workWebDrinking a lot of alcohol may cause your platelet level to drop. Toxic chemicals : Exposure to toxic chemicals, including arsenic, benzene and pesticides, may affect your platelet level. Medications : Antibiotics that treat bacterial infections, medication for seizures and heart conditions, and the blood thinner heparin may affect platelet levels. can i get ssi and have life insuranceWebDEPAKOTE can cause other serious side effects, including: Bleeding problems: red or purple spots on your skin, bruising, pain and swelling into your joints due to bleeding or bleeding from your mouth or nose. High ammonia levels in your blood: feeling tired, vomiting, changes in mental status. can i get ss from my husbandWebMar 1, 2024 · Propofol. Sodium Oxybate. Vorinostat. Warfarin. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. fit t shirts onlineWebNov 2, 2024 · Commonly reported side effects of divalproex sodium include: abdominal pain, asthenia, dizziness, drowsiness, nausea, vomiting, thrombocytopenia, and anorexia. Other side effects include: abnormality in thinking, alopecia, ataxia, nystagmus disorder, tremor, weight loss, fever, and skin rash. can i get spectrum tv without internet